第五十三条 有下列行为之一的，处五日以下拘留或者警告；情节较重的，处五日以上十日以下拘留，可以并处一千元以下罚款：
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It is difficult to know exactly when the shift from gelatine to agar occurred. As often happens for scientific breakthroughs, agar was likely adopted incrementally alongside the use of other growth media. In 1913, for example, the first diagnosis of Serratia marcescens as a human pathogen was made by growing it on agar as well as on potatoes.